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Acne Vulgaris – Physical Treatments

Glycolic Acid (Chemical Peel)

Class: Acid

Route: Topical

Indication: Comedonal acne, especially for deep set comedones

Typical Dosage: A series of 3 peels are usually performed at 6 week intervals using different concentrations. The first peel is applied at a concentration of 30% for 3 minutes. The second peel is at 40% for 3 minutes, and the 3rd peel is at 50% for 3 minutes. Of course adjustments are made to the concentration of glycolic acid and the duration of the treatment based on individual skin type and skin reactions.

Side Effects: You may experience some burning, stinging, and temporary redness when undergoing treatment with glycolic acid. It is important to avoid the sun for a week after the treatment.

Special Notes: Any potentially irritating topical creams, lotions, and gels must be avoided for 24 hours after undergoing a chemical peel.

Contraindications: None

Mechanism of Action: Due to its excellent capability to penetrate the skin, glycolic acid is used to improve the skin’s appearance and texture. It is effective for comedonal acne (whiteheads and blackheads). Once applied, glycolic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together. This allows the dead skin cells to “dissolve” revealing the underlying healthier, smoother, and brighter-looking skin.

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